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Standard BioTools Reports Fourth Quarter and Full Year 2025 Financial Results

BOSTON, Mass., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Standard BioTools Inc. (NASDAQ: LAB) (the “Company” or “Standard BioTools”) today announced financial results for the quarter and fiscal year ended December 31, 2025.

Recent Highlights:

  • Fourth quarter 2025 revenue from Continuing Operations of $23.8 million; Full Year 2025 revenue of $85.3 million
  • Fully operationalized over $40 million in previously announced annualized cost savings supporting path to positive adjusted EBITDA and adjusted cash flow exiting 2026
  • Approximately $550 million in cash & investments following the closing of the SomaLogic transaction on January 30, 20261 to fuel inorganic growth strategy

“We delivered a strong finish to the year with better-than-expected performance, driven by disciplined execution across the business,” said Michael Egholm, PhD, President and Chief Executive Officer of Standard BioTools. “Our team continued to deliver tangible efficiency gains, fully operationalizing over $40 million in previously announced cost savings and exiting the year with meaningfully lower run-rate operating expenses, reinforcing progress toward achieving our 2026 profitability targets.”

Dr. Egholm continued, “Looking ahead, we enter 2026 with a focused and streamlined business, a proven team executing with the rigor of the Standard BioTools Business System (SBS), a strong balance sheet following the strategic sale of SomaLogic to Illumina, and approximately $1 billion in NOL carryforwards. Taken together, these differentiated assets provide significant flexibility to pursue disciplined M&A and drive long-term shareholder value.”

Financial Results Table: Continuing Operations
 
  As Reported  
  Three Months Ended     Twelve Months Ended  
(Unaudited, in millions, except percentages) December 31, 2025     December 31, 2025  
Revenue $ 23.8     $ 85.3  
Gross margin   47.8 %     49.9 %
Non-GAAP gross margin   50.3 %     53.6 %
Operating expenses $ 36.0     $ 152.8  
Non-GAAP operating expenses $ 27.8     $ 108.3  
Operating loss $ (24.6 )   $ (110.2 )
Net loss from continuing operations $ 13.9     $ (58.8 )
Adjusted EBITDA $ (15.8 )   $ (62.6 )
Cash, cash equivalents, restricted cash, and liquid investments $ 210.7     $ 210.7  

1 This approximate cash and investments balance is unaudited and may be adjusted as a result of, among other things, completion of financial closing procedures and internal reviews. This financial information does not represent a comprehensive statement of the Company’s current financial results.

Fourth Quarter 2025 Financial Results: Continuing Operations

Following the announced sale of SomaLogic, Inc. (“SomaLogic”) and other specified assets to Illumina, Inc. (“Illumina”) in June 2025, which transaction closed in January 2026, all financial results in this section reflect continuing operations only.

  • Revenue was $23.8 million in the fourth quarter of 2025, down 4% year-over-year.
    • Consumables revenue was $9.0 million in the fourth quarter of 2025, down 17% year-over-year. Lower consumables revenue in the quarter reflected project funding declines primarily in flow and microfluidics.  
    • Instruments revenue was $8.5 million in the fourth quarter of 2025, up 10% year-over-year. Instrument revenue in the quarter reflected strong growth in imaging but overall remained impacted by capital-constrained end-markets, particularly in the Americas.
    • Services revenue, which is predominantly Field Services, was $6.4 million in the fourth quarter of 2025, up 1% year-over-year. Lab Services revenue increased due to higher demand from pharmaceutical customers, offset by decreased Field Services revenue due to fewer active service contracts and lower on-demand revenue driven by improved instrument quality and uptime.
  • Gross margins in the fourth quarter of 2025 were approximately 47.8%, versus 45.8% in the fourth quarter of 2024; and non-GAAP gross margins in the fourth quarter of 2025 were approximately 50.3%, versus 48.1% in the fourth quarter of 2024. Gross margins and non-GAAP gross margins were driven by volume and product mix.

  • Operating expenses in the fourth quarter of 2025 were $36.0 million, a decrease of $1.4 million, or down 4%, compared to the fourth quarter of 2024. Operating expenses included $2.1 million in restructuring and related charges. Non-GAAP operating expenses, which exclude transaction costs, stock-based compensation, and restructuring charges, were $27.8 million in the fourth quarter of 2025, a decrease of $0.4 million, or down 1%, compared to the fourth quarter of 2024. The decrease in operating expenses was due to restructuring actions.

  • Net income for the fourth quarter of 2025 was $13.9 million, compared to a net loss of $27.2 million in the fourth quarter of 2024, representing a change of $41.1 million or 151%. The improvement primarily reflects a one-time, non-cash partial release of $38.4 million of the U.S. deferred tax valuation allowance, based on expected gains from the Sengenics and SomaLogic divestitures and our conclusion that this portion will be realized. Adjusted EBITDA for the fourth quarter of 2025 was a loss of $15.8 million, versus an adjusted EBITDA loss of $16.2 million in the fourth quarter of 2024, an improvement of $0.4 million, or 3%.

Full Year 2025 Financial Results: Continuing Operations

Following the announced sale of SomaLogic and other specified assets to Illumina, in June 2025, which transaction closed in January 2026, all financial results in this section reflect continuing operations only.

  • Revenue was $85.3 million in 2025, down 6% year-over-year.
    • Consumables revenue was $36.2 million in 2025, down 11% year-over-year. Lower consumables revenue in the year reflected project funding declines in flow and microfluidics.
    • Instruments revenue was $25.4 million in 2025, up 2% year-over-year. Instrument revenue in the year reflected growth in imaging but overall remained impacted by capital-constrained end-markets globally.
    • Services revenue, which is predominantly Field Services, was $23.7 million in 2025, down 7% year-over-year. Lab Services revenue increased due to higher demand from pharmaceutical customers, offset by decreased Field Services revenue due to fewer active service contracts and lower on-demand revenue driven by improved instrument quality and uptime.
  • Gross margins in 2025 were approximately 49.9%, versus 49.3% in 2024; and non-GAAP gross margins in 2025 were approximately 53.6%, versus 53.3% in 2024. Gross margins and non-GAAP gross margins were driven by volume and product mix.

  • Operating expenses in 2025 were $152.8 million, a decrease of $19.6 million, or down 11%, compared to 2024. Operating expenses included $14.8 million in restructuring and related charges. Non-GAAP operating expenses, which exclude transaction costs, stock-based compensation, and restructuring charges, were $108.3 million in 2025, a decrease of $4.4 million, or down 4%, compared to 2024. The decrease in operating expenses was due to restructuring actions.

  • Net loss for 2025 was $58.8 million, compared to a net loss of $90.9 million in 2024, representing an improvement of $32.1 million or 35%. The improvement primarily reflects a one-time, non-cash partial release of $38.4 million of the U.S. deferred tax valuation allowance, based on expected gains from the Sengenics and SomaLogic divestitures and our conclusion that this portion will be realized. Adjusted EBITDA for 2025 was a loss of $62.6 million, versus an adjusted EBITDA loss of $64.2 million in 2024, an improvement of $1.7 million, or 3%.

  • Net operating loss (NOL) carry forwards of approximately $1 billion for US federal income tax purposes. Utilization of this NOL carry forward may be subject to expiration and substantial annual limitations.

Full Year 2026 Revenue Outlook

For fiscal year 2026, the Company expects revenue in the range of $80 million to $85 million, with seasonality similar to prior years.

Use of Non-GAAP Financial Information

Standard BioTools has presented certain financial information in accordance with U.S. GAAP and on a non-GAAP basis. The non-GAAP financial measures included in this press release are non-GAAP gross margin, non-GAAP gross profit, non-GAAP operating expenses, and adjusted EBITDA. Management uses these non-GAAP financial measures, in addition to GAAP financial measures, as a measure of operating performance because the non-GAAP financial measures do not include the impact of items that management does not consider indicative of the Company’s core operating performance. Management believes that non-GAAP financial measures, taken in conjunction with GAAP financial measures, provide useful information for both management and investors by excluding certain non-cash and other expenses that are not indicative of the Company’s core operating results. Management uses non-GAAP measures to compare the Company’s performance relative to forecasts and strategic plans and to benchmark the Company’s performance externally against competitors. Non-GAAP information is not prepared under a comprehensive set of accounting rules and should only be used to supplement an understanding of the Company’s operating results as reported under U.S. GAAP. Standard BioTools encourages investors to carefully consider its results under GAAP, as well as its supplemental non-GAAP information and the reconciliations between these presentations, to more fully understand its business. Reconciliations between GAAP and non-GAAP financial measures are presented in the accompanying tables of this release.     

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including, among others, statements regarding future financial and business performance, including with respect to the full year 2026 revenue outlook and expected cash following the closing of the transaction with Illumina; operational and strategic plans; deployment of capital; market and growth opportunity and potential; and the potential to realize the expected benefits from the transaction with Illumina and the expected benefits and synergies of prior and potential future acquisitions, including the potential for such transactions to drive long-term profitable growth. Forward-looking statements are subject to numerous risks and uncertainties that could cause actual results to differ materially from currently anticipated results, including, but not limited to, the potential that the expected benefits and opportunities of the transaction may not be realized or may take longer to realize than expected; risks that the anticipated benefits and synergies resulting from prior and potential future acquisitions and the integration of any such businesses, including the potential for such transactions to drive long-term profitable growth, may not be fully realized or may take longer to realize than expected; risks that the Company may not realize expected cost savings from such transactions; possible integration, restructuring and transition-related disruption resulting from such transactions, including through the loss of customers, suppliers, and employees and adverse impacts on the Company’s development activities and results of operation; integration and restructuring activities, including customer and employee relations, management distraction, and reduced operating performance; risks that internal and external costs required for ongoing and planned activities may be higher than expected, which may cause the Company to use cash more quickly than it expects or change or curtail some of the Company’s plans, or both; risks that the Company’s expectations as to expenses, cash usage, and cash needs may prove not to be correct for other reasons such as changes in plans or actual events being different than our assumptions; changes in the Company’s business or external market conditions; existing and potential future NIH funding pressures; the effect from existing and potential future U.S. export controls and tariffs; challenges inherent in developing, manufacturing, launching, marketing, and selling new products; interruptions or delays in the supply of components or materials for, or manufacturing of, the Company’s products; reliance on sales of capital equipment for a significant proportion of revenues in each quarter; seasonal variations in customer operations; unanticipated increases in costs or expenses; continued or sustained budgetary, inflationary, or recessionary pressures; uncertainties in contractual relationships; reductions in research and development spending or changes in budget priorities by customers; uncertainties relating to the Company’s research and development activities, and distribution plans and capabilities; potential product performance and quality issues; risks associated with international operations; intellectual property risks; and competition. For information regarding other related risks, see the “Risk Factors” section of the Company’s annual report on Form 10-K, for the year ended December 31, 2024, filed with the SEC on March 11, 2025, the Company’s quarterly report on Form 10-Q for the quarter ended June 30, 2025, filed with the SEC on August 15, 2025, and in the Company’s other filings with the SEC. These forward-looking statements speak only as of the date hereof. The Company disclaims any obligation to update these forward-looking statements except as may be required by law.

About Standard BioTools Inc.

Standard BioTools, Inc. (Nasdaq: LAB), is committed to setting the new standard in the life science tools industry through strategic consolidation, best-in-class operations and a world class management team. The Company's established portfolio includes essential, standardized next-generation solutions designed to help biomedical researchers develop better therapeutics faster. Learn more at standardbio.com or connect with us on X, Facebook®, LinkedIn, and YouTube™.

For Research Use Only. Not for use in diagnostic procedures.

Limited Use Label License and other terms may apply: standardbio.com/legal/salesterms.
Patent and License Information: standardbio.com/legal/notices.
Trademarks: standardbio.com/legal/trademarks. Any other trademarks are the sole property of their respective owners. ©2026 Standard BioTools Inc. (f.k.a. Fluidigm Corporation). All rights reserved.

Investor Contact:
ir@standardbio.com

STANDARD BIOTOOLS INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
Continuing Operations
(In thousands, except per share amounts)
(Unaudited)
 
    Three Months Ended
December 31,
    Twelve Months Ended
December 31,
 
    2025     2024     2025     2024  
Revenue:                        
Product revenue   $ 17,405     $ 18,442     $ 61,659     $ 65,429  
Services and other revenue     6,390       6,335       23,672       25,579  
Total revenue     23,795       24,777       85,331       91,008  
Cost of revenue:                        
Cost of product revenue     8,786       8,877       29,553       30,652  
Cost of services and other revenue     3,627       4,543       13,235       15,473  
Total cost of revenue     12,413       13,420       42,788       46,125  
Gross profit     11,382       11,357       42,543       44,883  
Operating expenses:                        
Research and development     7,969       7,040       25,987       28,831  
Selling, general and administrative     25,337       27,318       109,861       103,058  
Restructuring and related charges     2,075       126       14,782       12,500  
Transaction and integration expenses     645       2,955       2,162       27,979  
Total operating expenses     36,026       37,439       152,792       172,368  
Loss from operations     (24,644 )     (26,082 )     (110,249 )     (127,485 )
Bargain purchase gain                       25,213  
Interest income     1,662       3,896       9,179       20,199  
Interest expense     (5 )     (572 )     (26 )     (3,316 )
Other income (expense), net     956       (4,143 )     4,394       (5,008 )
Loss before income taxes     (22,031 )     (26,901 )     (96,702 )     (90,397 )
Income tax benefit (expense)     35,932       (272 )     37,876       (542 )
Net income (loss) from continuing operations     13,901       (27,173 )     (58,826 )     (90,939 )
Discontinued operations:                        
Income (loss) from discontinued operations, net of tax     5,382       (6,899 )     (16,070 )     (47,946 )
Net income (loss)   $ 19,283     $ (34,072 )   $ (74,896 )   $ (138,885 )
Induced conversion of redeemable preferred stock     -       -       -       (46,014 )
Net income (loss) attributable to common stockholders   $ 19,283     $ (34,072 )   $ (74,896 )   $ (184,899 )
Net income (loss) per share from continuing operations   $ 0.04     $ (0.07 )   $ (0.15 )   $ (0.39 )
Net income (loss) per share from discontinued operations   $ 0.01     $ (0.02 )   $ (0.04 )   $ (0.14 )
Net income (loss) per share attributable to common stockholders   $ 0.05     $ (0.09 )   $ (0.20 )   $ (0.52 )
Shares used in computing net income (loss) per share attributable to common stockholders     385,048       374,544       381,623       353,245  


STANDARD BIOTOOLS INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
Continuing Operations
(In thousands)
(Unaudited)
 
    December 31,
2025
    December 31,
2024
 
ASSETS            
Current assets:            
Cash and cash equivalents   $ 118,213     $ 166,728  
Short-term investments     69,362       126,146  
Accounts receivable, net     13,431       14,741  
Inventory     19,981       20,744  
Prepaid expenses and other current assets     4,871       4,561  
Current assets held for sale     228,406       42,963  
Total current assets     454,264       375,883  
Property and equipment, net     19,275       22,775  
Operating lease right-of-use asset, net     26,732       26,567  
Other non-current assets     3,154       3,550  
Long-term investments     25,701        
Deferred tax asset, non-current     38,628       138  
Non-current assets held for sale           183,432  
Total assets   $ 567,754     $ 612,345  
LIABILITIES AND STOCKHOLDERS' EQUITY            
Current liabilities:            
Accounts payable   $ 5,407     $ 5,049  
Accrued liabilities     29,783       21,435  
Operating lease liabilities, current     5,490       4,806  
Deferred revenue, current     38,949       10,274  
Deferred grant income, current     3,046       3,527  
Current liabilities held for sale     25,633       20,804  
Total current liabilities     108,308       65,895  
Convertible notes, non-current     299       299  
Deferred tax liability     810       1,081  
Operating lease liabilities, non-current     25,038       25,590  
Deferred revenue, non-current     3,503       32,674  
Deferred grant income, non-current     4,290       7,243  
Other non-current liabilities     1,215       1,062  
Non-current liabilities held for sale           6,779  
Total liabilities     143,463       140,623  
Total stockholders’ equity     424,291       471,722  
Total liabilities and stockholders’ equity   $ 567,754     $ 612,345  


STANDARD BIOTOOLS INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(In thousands)
(Unaudited)
 
    Twelve Months Ended
December 31,
 
    2025     2024  
Operating activities            
Net loss   $ (74,896 )   $ (138,885 )
Bargain purchase gain           (25,213 )
Stock-based compensation expense     29,613       31,732  
Amortization of acquired intangible assets     1,715       4,346  
Depreciation and amortization     9,262       12,515  
Accretion of discount on short-term investments, net     (2,653 )     (7,435 )
Non-cash lease expense     604        
Non-cash lease expense     6,019       5,766  
Provision for excess and obsolete inventory     3,468       2,524  
Change in fair value of warrants     (232 )     (632 )
Change in fair value of contingent consideration     (3,177 )      
Other non-cash items     905       1,025  
Changes in assets and liabilities, net     (44,978 )     (29,197 )
Net cash used in operating activities     (74,350 )     (143,454 )
Investing activities            
Cash and restricted cash acquired in the Merger           280,033  
Acquisition of business, net of cash acquired           (1,385 )
Purchases of short-term marketable debt securities     (101,753 )     (256,119 )
Purchases of long-term marketable debt securities     (32,321 )      
Purchases of marketable equity securities     (6,857 )      
Purchase of convertible note receivable     (5,000 )      
Proceeds from sales and maturities of investments     179,000       349,000  
Purchases of property and equipment     (8,303 )     (8,355 )
Net cash provided by (used in) investing activities     24,766       363,174  
Financing activities            
Repayment of term loan and convertible notes           (63,192 )
Payment of term loan fee           (545 )
Repurchase of common stock           (40,490 )
Proceeds from ESPP stock issuance     523       918  
Payments for taxes related to net share settlement of equity awards and other     (484 )     (459 )
Proceeds from exercise of stock options     531       1,152  
Net cash provided by (used in) financing activities     570       (102,616 )
Effect of foreign exchange rate fluctuations on cash and cash equivalents     842       (785 )
Net increase (decrease) in cash, cash equivalents and restricted cash     (48,172 )     116,319  
Cash, cash equivalents and restricted cash at beginning of period     168,818       52,499  
Cash, cash equivalents and restricted cash at end of period   $ 120,646     $ 168,818  
Cash, cash equivalents, and restricted cash consists of:            
Cash and cash equivalents   $ 118,213     $ 166,728  
Restricted cash     2,433       2,090  
Total cash, cash equivalents and restricted cash   $ 120,646     $ 168,818  


STANDARD BIOTOOLS INC.
REVENUE
Continuing Operations
(In thousands)
(Unaudited)
 
    Three Months Ended December 31,     Year Ended December 31,  
    2025     2024     2025     2024  
Product revenue:                        
Instruments   $ 8,455     $ 7,668     $ 25,411     $ 24,889  
Consumables     8,950       10,774       36,248       40,540  
Total product revenue     17,405       18,442       61,659       65,429  
Services and other revenue     6,390       6,335       23,672       25,579  
Total revenue   $ 23,795     $ 24,777     $ 85,331     $ 91,008  


STANDARD BIOTOOLS INC.
RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL INFORMATION
Continuing Operations
(In thousands)
(Unaudited)
 
ITEMIZED RECONCILIATION OF GROSS PROFIT TO NON-GAAP GROSS PROFIT AND MARGIN PERCENTAGE
 
    As Reported  
    Three Months Ended
December 31,
    Twelve Months Ended
December 31,
 
    2025     2024     2025     2024  
Gross profit   $ 11,382     $ 11,357     $ 42,543     $ 44,883  
Amortization of acquired intangible assets                       1,407  
Depreciation and amortization     145       277       1,552       1,294  
Stock-based compensation expense     431       295       1,461       896  
Loss on disposal of property and equipment                 187        
Non-GAAP gross profit   $ 11,958     $ 11,929     $ 45,743     $ 48,480  
                         
Gross margin percentage     47.8 %     45.8 %     49.9 %     49.3 %
Amortization of acquired intangible assets                       1.6 %
Depreciation and amortization     0.6 %     1.1 %     1.8 %     1.4 %
Stock-based compensation expense     1.9 %     1.2 %     1.7 %     1.0 %
Loss on disposal of property and equipment                 0.2 %      
Non-GAAP gross margin percentage     50.3 %     48.1 %     53.6 %     53.3 %


STANDARD BIOTOOLS INC.
RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL INFORMATION
Continuing Operations
(In thousands)
(Unaudited)
 
ITEMIZED RECONCILIATION OF GAAP TO NON-GAAP OPERATING EXPENSES
 
    As Reported  
    Three Months Ended
December 31,
    Twelve Months Ended
December 31,
 
    2025     2024     2025     2024  
Operating expenses   $ 36,026     $ 37,439     $ 152,792     $ 172,368  
Restructuring and related charges (1)     (2,075 )     (126 )     (14,782 )     (12,500 )
Transaction and integration expenses     (645 )     (2,955 )     (2,162 )     (27,979 )
Stock-based compensation expense     (4,386 )     (5,489 )     (22,101 )     (16,515 )
Depreciation and amortization     (1,142 )     (655 )     (5,428 )     (2,600 )
Loss on disposal of property and equipment     (10 )     (48 )     (10 )     (75 )
Non-GAAP operating expenses   $ 27,768     $ 28,166     $ 108,309     $ 112,699  
                         
R&D operating expenses   $ 7,969     $ 7,040     $ 25,987     $ 28,831  
Stock-based compensation expense     (600 )     (655 )     (1,917 )     (1,702 )
Depreciation and amortization     (184 )     (144 )     (1,181 )     (581 )
(Loss) gain on disposal of property and equipment     (7 )     (3 )     21       (3 )
Non-GAAP R&D operating expenses   $ 7,178     $ 6,238     $ 22,910     $ 26,545  
                         
SG&A operating expenses   $ 25,337     $ 27,318     $ 109,861     $ 103,058  
Stock-based compensation expense     (3,786 )     (4,834 )     (20,184 )     (14,813 )
Depreciation and amortization     (958 )     (511 )     (4,247 )     (2,019 )
Loss on disposal of property and equipment     (3 )     (45 )     (31 )     (72 )
Non-GAAP SG&A operating expenses   $ 20,590     $ 21,928     $ 85,399     $ 86,154  
  1. Restructuring and related charges for the twelve months ended December 31, 2025 includes $2.2 million of stock-based compensation expense.

STANDARD BIOTOOLS INC.
RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL INFORMATION
Continuing Operations
(In thousands)
(Unaudited)
 
ITEMIZED RECONCILIATION OF GAAP NET LOSS TO ADJUSTED EBITDA
 
    As Reported  
    Three Months Ended
December 31,
    Twelve Months Ended
December 31,
 
    2025     2024     2025     2024  
Net loss   $ 13,901     $ (27,173 )   $ (58,826 )   $ (90,939 )
Income tax (benefit) expense     (35,932 )     272       (37,876 )     542  
Interest income     (1,662 )     (3,896 )     (9,179 )     (20,199 )
Interest expense     5       572       26       3,316  
Amortization of acquired intangible assets                       1,407  
Depreciation and amortization     1,287       932       6,980       3,894  
Bargain purchase gain                       (25,213 )
Restructuring and related charges     2,075       126       12,570       12,500  
Transaction and integration expenses     645       2,955       2,162       27,979  
Stock-based compensation expense (1)     4,817       5,784       25,774       17,411  
Loss on disposal of property and equipment     10       48       197       75  
Other non-operating (income) expense     (956 )     4,143       (4,394 )     5,008  
Adjusted EBITDA     (15,810 )     (16,237 )     (62,566 )     (64,219 )
  1. Stock-based compensation expense for the twelve months ended December 31, 2025 includes $2.2 million of expense that is allocated to restructuring and related charges on the Company’s consolidated statement of operations.

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